I had a client today with a few vision problems. The small fonts and certain colors were difficult for him to see.
Hold CTRL+(+ key) to increase font size adn hold CTRL+(- key) to decrease the font size. However, this change is only temporary.
To make more permanent changes to the font size go into Tools->Options and select the Content tab. You can make changes on that main screen and under the Advanced button.
Oh heck - just watch the video below (click "read more if the video isn't already showing), it makes more sense that way.
Links:
[1] https://www.paypal.com/cgi-bin/webscr?cmd=_xclick&business=rick@yourpcpartner.com&item_name=Buy
[2] http://www.helpmerick.com/node/1398
[3] http://www.helpmerick.com/node/1395